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Given the negative surface charge and absence of targeting ligands, our nanocarrier is unlikely to utilize receptor or adsorptive-mediated transcytosis

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Indeed, recommendations to incorporate the use of imaging and fluid biomarkers as part of the diagnosis on a broader scale has been recommended by newer National Institute on Aging and the Alzheimers Association working groups [65, 98, 99] would help to characterize endogenous antioxidant changes in early stages of disease and offer insight into GSHs potential as a therapeutic target

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